AI for Scientific Research
otto-SR helps scientific research teams search the literature, extract verifiable evidence, and synthesize findings with human oversight at every step. Peer-reviewed in the Annals of Internal Medicine.
Trusted by leading researchers & guideline groups
Use cases
Rigorously interface with clinical evidence
otto-SR turns the scientific literature into structured, verifiable analyses that deliver strategic intelligence, regulatory evidence, and market insights your teams can defend.
Regulatory submissions
Audit-ready submission & HTA evidence.
Build defensible, audit-ready evidence packages for regulatory submissions and health technology assessments
otto-SR supported a biopharmaceutical company’s EU-MDR submission by screening over 30,000 citations across global databases, including non-English sources such as Chinese medical literature. We tripled the team’s search coverage and delivered results in days instead of months.
- +200% database search size vs the team's manual approach
- 30,000+ citations screened across global databases in one engagement
- Global non-English sources, including Chinese medical literature
- Days turnaround instead of months with traditional methods
What clients say
“Healthcare providers, policymakers, and others often must wait 6 to 12 months for systematic reviews, which is not helpful when timely decisions are needed. otto-SR is the answer. I'm so glad I found it — I use it for all my systematic reviews. otto-SR provides reliable, robust evidence quickly. It's intuitive, easy to use, and I believe it will soon become the standard for conducting systematic reviews.”
David Moher, PhD
Founder of PRISMA Guidelines
University of Ottawa
“Working with the otto-SR team has been a highlight for our group. otto-SR completed two of our systematic reviews, identifying all studies we had found while also uncovering additional potentially relevant studies. This rapid verification gave us confidence that nothing was missed, which was invaluable prior to publication. Moving forward, we hope to use otto-SR to further streamline our process and improve efficiency.”
Andrea Tricco, PhD
PRISMA-ScR Lead
Unity Health Toronto
“We were impressed with how otto-SR's platform streamlined the initial, quite time-consuming phase of this process. The system efficiently screened over 30,000 citations, saving our team many months of manual effort. Most importantly, the platform successfully surfaced a high number of relevant studies.”
Martin Juhl, PhD
Chief Scientific Officer
Cessatech
“As a clinician-scientist, I regularly conduct systematic reviews to inform clinical practice — work that traditionally demands large teams and months of coordinated effort. otto-SR represents a genuine paradigm shift. By dramatically accelerating evidence synthesis, it enhances research productivity and speeds the translation of evidence into action. Where I once couldn't imagine AI doing this for us, I can no longer imagine a world without it.”
Kieran Quinn, MD, PhD
Clinician Scientist
University of Toronto
“It would have taken our small team months to complete, even with very streamlined extraction steps. otto-SR completed extraction in under a week. Ultimately, it let me spend a lot more time on interpreting analyses, writing, and thinking through the more complex parts of the paper with evidence-informed results to guide it.”
Mairead Whelan, MPhil
Researcher
Oxford University
“otto-SR allowed us to complete in roughly two weeks what would normally take months, while maintaining methodological rigor. It captured all previously included studies and maintained high agreement with our human reviewers. It also identified additional eligible studies we had missed. It would be difficult to go back to the traditional fully manual approach after using it.”
Gregory Hundemer, MD, MPH
Clinician Scientist
University of Ottawa
Peer-reviewed results
Better-than-human performance
otto-SR delivers state-of-the-art performance across abstract screening, full-text review, and data extraction, with peer-reviewed results benchmarked against both humans and competing systems.
between otto-SR, humans, and competitors
Capabilities
One platform across the research lifecycle
Search through the metadata of over 500 million research articles.
Integration with Retraction Watch flags retracted studies before they enter your review.
Security
Enterprise-grade security and controls
otto-SR meets the highest industry standards for security and compliance.
Independent assurance that our controls protect customer data across security, availability, and confidentiality.
International standard for information security management systems.
Your data is never stored on or used to train AI models. All data can be purged on demand.